Download Citation on ResearchGate | Clonixinato de lisina mg versus diclofenac 75 mg en el tratamiento del dolor cólico renal Ensayo clínico prospectivo. MASTER FARMA S.A., MEDICINA, PRODUCTOS, DORIXYL – CLONIXINATO DE LISINA, antiinflamatorios, los antiinflamatorios no esteroideos, impidiendo la. Many translated example sentences containing “clonixinato de lisina” – English- Spanish dictionary and search engine for English translations.

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The treatment of somatic and visceral pain syndromes. Hypersensitivity to Clonixinate Lysine. It is contraindicated when either active peptic or duodenal ulcer are present.

Its mechanism of action is developed by inhibiting the synthesis of prostaglandins, specifically on the catalytic enzyme of the synthesis of prostaglandins that mediate inflammation cyclooxygenase-2 or COX-2with less activity on the catalytic enzyme of the synthesis of prostaglandins in the gastrointestinal mucus and kidneys Cyclooxygenase-1 or COX-1where these substances have a protective function.

This drug has a half life of 90 minutes, and is metabolized primarily in the liver, distributing the metabolites through the blood vessels, and is eliminated through the kidneys. Initial response on the application: When taken orally, analgesic effect is achieved within 15 to 30 minutes.

Duration of a single oral dose effect: Four hours for headaches.

Clonixinato de lisina Sanderson

lisia Orally, the therapy concentration peak was reached in 15 minutes. The concentration peak was Pediatric volume of distribution 1. Values obtained in children 4 to 10 years of age. It is metabolized lksina the liver forming hydroxylated and hydroxymethylized metabolites activities are unknown. The elimination occurs after minutes. Ljsina not be administered to pregnant or nursing women. Not recommended for children under 12 years of age. May increase the risk of toxicity in elderly patients.

Closely monitor when administered with other medications such as anticoagulants, Aspirin and cephalosporins that may induce hypoprothrombinemia; on the other hand, monitor cyclosporine, lithium, methotrexate, plicamycin, probenecid, triamterene, and valproic acid.

Do not take more than the prescribed or recommended dose. Clonixinago you miss the recommended dose, which may be one or two times a day, take it as soon as possible within the first two se. Do not take it close to the next one this will double the dose.


Due to its content of lactose, intolerance have been reported in children and adolescents, although because of the amount of lactose present in the preparation it is unlikely to trigger symptoms of intolerance, in which case you should consult your doctor. Information on the Active Ingredient: A controlled three-year clinical trial in 2, patients most of whom received NSAIDs, the incidence of gastrointestinal adverse effects were similar to those developed in patients receiving Alendronate and those receiving a placebo.

It is not cloinxinato to administer Alendronate and NSAIDs simultaneously since they have been associated with gastrointestinal irritation. The mechanism involves attenuation of the antihypertensive effect of the secondary agent in the production of vasodilator and natriuretic prostaglandins, which are stimulated by antihypertensive agents.

Clonixinato de lisina

There is no known significant pharmacokinetic interaction between NSAIDs and Angiotensin Converting Enzyme, and its combination may produce effects such as bradycardia due to hyperkalemia. Patients suffering from hypertension, diabetes ckonixinato, ischemic heart disease and degenerative diseases linked to the above must be careful when taking the combination of these drugs.

Usually associated with an increased risk of gastrointestinal bleeding.

NSAIDs decrease the antihypertensive and natriuretic effect of Angiotensin Converting Enzyme inhibitors, particularly in low renin hypertensive patients. The Loop of Henle diuretics act by active inhibition in the lsina of chloride in the Loop of Henle and increase renal blood flow.

They may also cause hyperkalemia or even nephrotoxicity if used concurrently.

Clonixinato de lisina Mintlab –

May cause anuria, oliguria, or acute kidney failure if administered with Ibuprofen. Not to be given to patients with peptic ulcer or patients predisposed or with pre-existing nepho-therapy and acute kidney dysfunction. Patients should make regular visits to their specialist during prolonged therapy. Alcohol use increases the risk of ulceration; consult the specialist if you drink three clonixinnato more alcoholic beverages. While lixina toxicology studies have shown no teratogenic effects, there is insufficient experience with the administration of Lysine Clonixinate in pregnant women and, therefore, should not be administered during this period.


There are no clinical studies on the administration of Clonixinate Lysine to children under 12, thus, its use is contraindicated for them. As with all anti-inflammatories, Lysine Clonixinate should be administered with caution to elderly patients as they may have impaired kidney, liver or cardiovascular function. The main side effects in therapeutic treatment are gastrointestinal in nature nausea, vomiting, epigastric pain.

There are other side effects that affect dde central nervous system headache, dizziness, drowsiness and, occasionally, skin reactions. Side effects at blood level are: Was observed in 9 volunteer clonizinato who were given mg of Lysine Clonixinate three times daily for three days.

Occurred in one out of every patients treated with mg of Lysine Clonixinate after minor dental surgery.

Occurred in one of patients treated with mg of Lysine Clonixinate. Side effects to the central nervous system: Vertigo, dizziness, drowsiness, euphoria, fatigue, headache, insomnia, tremor. Diarrhea, dry mouth, epigastric pain, flatulence, gastrointestinal disturbances, heartburn, nausea, vomiting. Diaphoresis excessive dry skinflushing or redness, irritation when applied parenterallyitching, pruritus, urticaria. Should not be administered to patients with renal dysfunction, cholestasis and paresthesia.

In the event of clonixnato overdose, go immediately to the nearest hospital. After a clinical evaluation of the patient, the specialist will decide the appropriate treatment: Self-induced vomiting or emesis, gastric lavage or administration of activated charcoal.

There is no specific antidote. Dose for adults and children over 12 years: Take the coated tablets whole without chewing, and with plenty of water.

Keep away from heat and sunlight. Boxes of 20, 48, 60, 80 and tablets in blisters of 4 coated tablets. Dispenser of tablets in blisters of 4 coated tablets.

Envelope of 4 coated tablets in blisters. Combinations with other drugs:.