ESTUDIO WHI, REVISTA DE MENOPAUSIA, SALUD, REVISTAS MÉDICAS. Actualidad Inmediata Debido a la importancia de esta investigación y al impacto en. WHI. Progestin. Estrogen. Tibolone. Cardiovascular disease. Tromboembolic disease . Boletín de la Asociación Española para el Estudio de la Menopausia, . Los trastornos de la menopausia pueden ser evitados y combatidos Sin embargo, recientes estudios, como el estudio WHI, han puesto en duda los beneficios.

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The effect of isoflavones extracted from red clover Rimostil on lipid and baile metabolism. Changes in symptoms, lipid and hormone levels after the administration of a cream with phytoestrogens in the climateric: Relationships of urinary phyto-estrogens excretion to BMD in postmenopausal women.

Third, the results of a crucial study should preferably be expressed in such a way that practitioners may use them for their practice to inform users. Continuing navigation will be considered as acceptance of this use. Hum Reprod, 16pp. It was meant to prove the clinical effectiveness of ONE specific estrogen and progestin to prevent whii disease. The WHI is an important study.

Isoflavonas y menopausia | Clínica e Investigación en Ginecología y Obstetricia

J Nutr,pp. The recommendation of WHI Committee is that continuous estrogen plus progestin should not be used even for the primary prevention of heart disease, and that they only should be used for the relief of vasomotor symptoms! This was the case with the WHI, a study aimed at the primary prevention of cardiovascular diseases in healthy postmenopausal women. Br J Nutr, 89pp.

Although there are no results yet from this ongoing study, it already carries an important message. The Women’s Health lnitiative lnvestigators. High quality observational studies may extend evidence over a wider population and are likely to be dominant in the identification of harms [ 8 ]. Unlike HERS which showed no benefit or harm after 6. It demonstrates a post-factum change in perceptions about the potential effects of HT on cognitive brain function and brain aging.


There is no reason to avoid postmenopause hormone medication when estduio and not contra-indicated. Strengths of WHIMS-Y include balance in baseline risk factors between treatment groups, standardized and masked data collection, and high rates of retention and on-trial adherence and exposure.

It seems that the recommendations of the WHI writing group are mainly focused on public rather than individual health, since they say that, even small individual risks over time, and on a population-wide basis, add up to menoopausia of thousands of those serious adverse health events and becomes an important public health concern. Principal results from the Women’s Health Initiative controlled randomized trial. Dietary soy has both beneficial and potencially adverse cardiovascular effects: Menopausal estrogen and estrogen-progestin replacement therapy and breast cancer risk.

Breast cancer risk following long-term oestrogen and oestrogen-progestin replacement therapy.

Clinical effects of standardized soy extract in postmenopausal women: This is a sign of excessive dose for women between Estos datos fueron publicados en una serie de manuscritos durante el periodo — Am J Cardiol ; 90 1 Supl.

Isoflavone rich esthdio protein isolate attenuates bone loss in the lumbar spine of perimenopausal women. Dietary intake of phytoestrogens is associated with a favorable metabolic cardiovascular risk profile in postmenopausal US women: Serum enterolactone concentration is not associated with breast cancer risk in a nested casecontrol study.

Effects of estrogen plus progestin on health-related quality of life. Trends in the incidence of coronary heart disease and changes in diet and lifestyle in women.

The order of magnitude of the relative risks is impressive. The effect eztudio a soy rich diet on the vaginal epithelium in postmenopause: Folia Clin Intern, 49pp. Menopause, 7pp. WHI does not introduce new rules to good clinical practice. The WHI decision to stop the estrogen progestin arm does not necessarily change a wise clinician’s decision as to the best clinical care of a postmenopausal woman. Thus this fixed excessive dose for older women does not necessarily reflect optimal good clinical practice and is not followed by any responsible gynaecologist.


The Nurses’ Health Study and studies from Europe, where estradiol is the commonly prescribed form of estrogen, suggest that the estrogen at lower doses may confer similar benefit” [ 15 ] Luckily one has nowadays an ample choice of strategies and drugs hormonal and non-hormonal that enable a conscientious physician to do his best to restore the confidence of those women who have sought his help. What is important is the best possible approach to preventive medicine in a mid-aged woman.

Recommend the use of any HRT to women with climacteric symptoms likely to impact on quality of life and to re-emphasize that topical use of low dose vaginal estrogens can be used by any woman estudik an indication for such therapy.

Fertil Steril, 77pp.

In addition, estrogen plus progestin therapy did not prevent mild cognitive impairment in these women. Phytoestrogens supplements for the treatment of hot flashes: In a re-analysis of HERS follow-up during 6.

JAMA,pp. Evaluation of soy phytoestrogens for the treatment of hot flashes in breast cancer survivors: Where are we now? J Bone Miner Res, 16pp.

The second was whether hormone use by younger postmenopausal women near the time of menopause reduces dementia risk or whether WHIMS findings should be generalized to younger women. Furberg CD, et al. Efficacy of a soy rich diet in preventing postmenopausal osteoporosis.