Hiponatremia y síndrome de secreción inadecuada de ADH (SIADH) La hiponatremia en la insuficiencia cardíaca: fisiopatología y enfoque farmacológico . Transcript of SIADH HIPONATREMIA. N E F R O L O G Í A CENTRO MÉDICO NACIONAL, 20 DE NOVIEMBRE. ISSSTE ÍNDROME DE S. antidiuretic hormone (SIADH) is the most frequent cause of hyponatraemia in hospital SIADH is the clinical and biochemical manifestation of a wide range of .
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The neurohypophysis, or posterior pituitary gland, produces two hormones: AVP acts on fiwiopatologia renal tubules to induce water retention, leading to concentration of the urine.
Oxytocin stimulates postpartum milk letdown in response to suckling. Its physiologic role in parturition is not established. Clinical syndromes may result from deficiency or sixdh of AVP.
AVP deficiency is characterized by production of large amounts of dilute urine. In gestational DIincreased metabolism gisiopatologia plasma AVP by an aminopeptidase vasopressinase produced by the placenta leads to a relative deficiency of AVP during pregnancy.
Primary polydipsia results in secondary insufficiency of AVP due to physiologic inhibition of AVP secretion by excessive fluid intake. Nephrogenic DI is caused by AVP resistance in the kidney; it can be genetic or acquired from drug exposure lithium, demeclocycline, amphotericin Bmetabolic conditions hypercalcemia, hypokalemiaor renal damage.
[Hyponatremia and syndrome of inappropriate ADH secretion (SIADH)].
Clinical or laboratory signs of dehydration, including hypernatremia, occur only if the pt simultaneously has a thirst defect not uncommon in pts with CNS disease or does not have access to water. Other etiologies of hypernatremia are described in Chap.
DI must be differentiated from other etiologies of polyuria Chap. Unless an inappropriately dilute urine is present in the setting of serum hyperosmolality, a fluid deprivation test is used to make the diagnosis of DI. This test should be started in the morning, and body weight, plasma osmolality, serum sodium, and urine volume and osmolality should be measured hourly.
Occasionally, hypertonic saline infusion may be required if fluid deprivation does not achieve the requisite level of hypertonic dehydration, but this should be administered with caution. This div only appears when the trigger link is hovered over. Otherwise it is hidden from view. About MyAccess If your institution subscribes to this resource, and you don’t have a MyAccess Profile, please contact your library’s reference desk for information on how to gain access to this resource from off-campus.
SIADH HIPONATREMIA by Gandhi Thomas Fonseca on Prezi
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