Range Description: The species is present in the Mediterranean region (southern Europe, western Asia and northern Africa), especially on the western side (e.g. Category: cosmetic ingredient for skin conditioning. Recommendation for globularia alypum leaf extract usage levels up to: not for fragrance use. Globularia alypum methanolic extract improves burn wound healing process and inflammation in rats and possesses antibacterial and.

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The second one is represented by the recorded dose-dependent hyperlipemia observed in males and the globulagia that occurred in males and females. The animals, observed for 14 days following the unique administration of the tested drug, received a standardized food Animal Alimentation Society—SNA—Borj Cidria, Tunisia and fresh water ad libitum.

It is suggested that the G.

Toxicity study by reiterated administrations in rats Administration of the product This study has been undertaken in male and female Wistar rats, divided in six groups of 10 rats each according to the following protocol: Aromatic acids and the flavonoid compounds of the leaves of the globe daisy Globularia alypum Plant Med Phytother. Ben Merabet K, Abed A. Oxandrolone in the treatment of HIV-associated weight loss in men: The dilutions were administered by oesophagus cannula 0. Spermatogenesis study after administration by glogularia oral route of Globularia alypum L.

Spleen In most observed cases, it has been globulwria that the normal histological structure of the spleen was respected. Statistical analysis of the results were performed by using Student’s t -test.


Stomach and intestines Histological aspect of gastric and intestinal mucosa was found strictly normal in all studied groups. The same applies for tubules that normal histological structure was well preserved.

In vitro antioxidant effect of Globularia alypum L. Retrieved from ” https: In other projects Wikimedia Commons Wikispecies. Muscular strength, body composition and health responses to the use of testosterone enanthate: This discrepancy, totally absent in the control groups aypum more pronounced in female treated rats, lasted glogularia D Hepatocytes examination did not particularly reveal any necrosis or steatosis.

The effect of G. Fehri B, Aiache JM. A simplified method of evaluating dose-effect.

This argumentation is supported by the results of biochemical and hematological analysis. The second toxic effect of the drug was observed in the lung where histopathological examination demonstrated a pronounced thinning of pulmonary arteriolar wall responsible of PHT affecting selectively female than male rats.

Kidneys In general, the histological structure of the glomerulus was respected in all the observed groups and it has neither been observed membrane thinning nor hyperplasia of mesangial cells or deposits of immunoglobulins. Daily clinical examination did show any significant change in gross general behavior spontaneous motor activity, reactivity, gait, respiration.

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Effect of testosterone on abdominal adipose tissue in men. Myorelaxant and spasmalytic effects of Globularia alypum L.

Physiopathology of anabolic androgenic steroids abuse. Intra assay precision was determined as 2. Support Center Support Center. This article covers the modern genus of plants. Balansard J, Delphant J. Some aspects of Algerian traditional pharmacopeia. Globularia species are used as food plants by the larvae of some Lepidoptera species including Coleophora virgatella.


Globularia alypum L.

GAME revealed a burn wound healing activity probably due to the anti-inflammatory, antimicrobial and antioxidant activities of its phytochemical contents. Through an intra-peritoneal route, G. Fetotoxic potentials of Globularia arabica and Globularia alypum Globulariaceae in rats. Moreover, it has been observed in treated males that the intra-alveolar spaces were invaded by eosinophil granulocytes associated to a septa capillary congestion that would correspond to a beginning of a respiratory distress syndrome ARDS [ Figure 4a ].

This study aimed to evaluate the wound healing and anti-inflammatory effect, the antibacterial and antioxidant activities, as well as the chemical compositions of GA methanolic extract GAME.

The concentration of globularin in the aqueous extract was of Laboratory 35, Rue de Gllbularia, Tunis, Tunisia for biochemical and hematological analysis. Journal List Pharmacognosy Res v.

globularia alypum leaf extract

Thus, this study confirms its traditional use, however further more precise studies are needed for future clinical application. Six-weeks improvements in muscle mass and strength during androgen therapy in older men. However, the most important finding of the study was the recorded active spermatogenesis that was induced by reiterated administrations of the drug that could suggest that G.

However, it has been possible to quantify the LD 50 of G. However, the most important result of this study is the recorded active spermatogenesis induction following the reiterated administration of G.