Dr. William Heberden, a London physician, described the first cases of Henoch- Schönlein purpura (HSP) in In describing HSP, Heberden wrote of a. Henoch-Schönlein purpura (HSP) affects the blood vessels and causes a spotty rash. It’s not usually serious, but can sometimes lead to kidney problems. Henoch–Schönlein purpura (HSP) is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children. In the skin.

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This may occur in the first week or so of the henodh, but there may be a delay of weeks or months before it appears. Typical purpura on lower legs and buttocks. How is HSP treated? It is dangerous to give more than the recommended dose. Retrieved from ” https: Serious kidney problems don’t happen very often, but they can occur. Coping with treatment and hospital. Skin biopsies will frequently show a leucocytoclastic vasculitis meaning lots of white blood cells in the skin around small blood vessels schonlrin the biopsy needs to be sent off to have a special test to find the IgA antibodies in the skin.

Get medical advice quickly if the symptoms come back. This page was last edited on 13 Decemberat Long term protection heenoch kidney function may require certain blood pressure lowering drugs see below.


Women with a history of HSP schonlsin become pregnant are at higher risk for high blood pressure and proteinuria during pregnancy. Not everyone gets all these symptoms, but the rash is a common accompaniment to other organ involvement.

Return to your doctor or the hospital sconlein your child has one or more of the following or if you are worried for any other reason:. Systemic lupus axalah Subacute bacterial endocarditis Rheumatoid arthritis. Antibody deposits on the skin can confirm the diagnosis of HSP.

What are the symptoms of HSP? Skin manifestations are more variable in adults, and sometimes symptoms in adults endure longer [Figure 1, 2]. It is believed that similar abnormalities may underlie HSP. As with all forms of inflammation, there may be complete resolution or there may be scars that form — on the skin or in the kidney.

Henoch-Schönlein Purpura

This is caused by inflammation and swelling of the small blood vessels in the skin. Cyclophophamide has also been used. Your feedback has been submitted successfully. We will respond to all feedback.

Granulomatosis with polyangiitis and microscopic polyangiitis can also present with purpura, arthritis, and renal inflammation. You’ll usually be asked to provide a sample of pee and have your blood pressure checked at each appointment. Fortunately, HSP usually gets better without any treatment. It usually passes in a few weeks and you can normally just rest at home until you feel better.


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About Vasculitis

This inflammation is called vasculitis. This image shows what the lining of the bowel shconlein look like when it is inflamed and swollen, as in HSP. In older patients kidney function may have been severely damaged and dialysis may be occasionally need to be initiated. Your baby’s first year.

Journal of the American Society of Nephrology. There is some evidence that steroid treatment may lead to more rapid improvement of bowel symptoms in children, as well as clearing up the rash.

Henoch-Schönlein Purpura • Johns Hopkins Vasculitis Center

Check here for alerts. Your doctor will want to check urine samples and blood pressure several times after the HSP goes away to check for kidney problems.

Important You can get HSP more than once. Recent research has shown corticosteroids—medications that decrease swelling and reduce the activity of the immune system—to be even more effective in treating joint pain. Any kidney problems usually get better without treatment.

Hemolytic disease of the newborn.

Autism spectrum disorder ASD.